Get ready for a night of laughter as matt Kirshen takes the stage at Helium Comedy Club - St. Louis on January 14, 2026. This talented comedian is known for his sharp wit and engaging storytelling, making it a must-see event for fans of stand-up. Later that month, Nine Inch Nails will electrify the Enterprise Center on February 25, 2026, bringing their iconic sound to the forefront for an unforgettable experience. If you’re in the mood for something more rock-oriented, catch Powerman 5000 at The Sovereign on May 5, 2026, where their high-energy performance is sure to rock the house. Just days before that, Christopher Cross will grace The Factory - Chesterfield on March 1, 2026, delivering his timeless hits that have resonated through generations. And don’t miss Chelsea Handler’s return to The Factory - Chesterfield on April 24, 2026, as she brings her unique brand of humor that fans have come to love. Explore more about each performer and venue to find the perfect experience for your night out in St. Louis. For all your event needs, saintlouis-tickets.com is your go-to source for the latest updates and ticket availability!